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  Cannabis Derivative Drugs May Be Made Available
Posted by FoM on February 17, 2002 at 20:58:19 PT
By James Meikle, Health Correspondent 
Source: Guardian Unlimited 

medical The government is clearing the way for the introduction of cannabis derivatives as NHS medicines to treat multiple sclerosis and relieve pain after operations if trials of two drugs prove successful.

The Department of Health is to ask the national institute for clinical excellence (Nice) to begin assessing next year whether the treatments are effective and worth the money they might cost the NHS. Ministers will today announce consultations on the scheme.

The painkillers might be available on prescription in 2004 or 2005 if the process of trials, licensing and NHS approval is completed on time.

One drug, cannabis-based medicinal extract, is an under-the-tongue spray being tested by GW Pharmaceuticals; the other is a tablet called Dronabinol, manufactured by Solvay Healthcare. Neither is expected to give the "high" enjoyed by cannabis smokers.

There have been anecdotal claims for years that smoking, infusing or eating cannabis can alleviate symptoms of MS including spasm, incontinence and pain.

The new drugs may also help treat nausea, leading to speculation that cannabis derivatives could provide treatments for a wider range of medical conditions.

The health analyses are being undertaken at the same time as a wider debate within government and police forces over the criminal uses of dope.

The home secretary, David Blunkett, is downgrading cannabis from a Class B to a Class C drug. While it still carries a possible two-year jail penalty for possession, a softly softly approach to its use has been controversially piloted in Lambeth, south London.

There are thought to be about 85,000 people in Britain with MS, a disabling disease of the nervous system.

David Harrison, spokesman for the Multiple Sclerosis Society, said yesterday: "If we are in a situation where we are going to have drugs approved which look as if they have a significant effect on helping alleviate symptoms, and it has been shown they can be safely used, we would want people to have access to them as soon as possible."

But he issued a note of caution about the anecdotal evidence. "We know a lot of people who say 'cannabis is wonderful; nothing else does this job for me'. You hear less about those who try it and get horrible reactions.

"We have always said people who are using it for medicinal purposes should be treated sympathetically."

The drugs which are being tested will need to be licensed by the government's medicines control agency. But there has been criticism that Nice, which must then decide whether the NHS should support the use of the drugs, holds up the process for making drugs available after that stage.

Running its assessment in parallel to the licensing procedure for the cannabis drugs should lead to such "Nice-blight" being avoided.

The Nice assessments will begin in April 2003 after some drugs trial results are available. Consultation on what should be in next year's programme starts today. Treatments for dementia, hepatitis C and leg ulcers are among others proposed by the health department. Nice decisions only directly affect the NHS in England and Wales but it is unlikely Scottish or Northern Ireland health authorities would refuse to back the cannabis drugs if they were supported elsewhere.

Special Report: Drugs in Britain: http://www.guardian.co.uk/drugs/0,2759,178206,00.html

Complete Title: Cannabis Derivative Drugs May Be Made Available To MS Sufferers

Source: Guardian Unlimited, The (UK)
Author: James Meikle, Health Correspondent
Published: Monday, February 18, 2002
Copyright: 2002 Guardian Newspapers Limited
Contact: letters@guardian.co.uk
Website: http://www.guardian.co.uk/

Related Articles & Web Site:

UK Medicinal Cannabis Project
http://www.medicinal-cannabis.org/

Cannabis & Pain Management
http://freedomtoexhale.com/drr.htm

Drug Laws Revolution Set for UK
http://cannabisnews.com/news/thread12030.shtml

Cannabis Pills on the NHS 'in Two Years'
http://cannabisnews.com/news/thread12029.shtml


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Comment #3 posted by bruce42 on February 18, 2002 at 11:29:31 PT
it's an image thing
western medicne comes in prescribed pill form. you are right in thinking that there is nothing wrong withthe plant itself, but western doctors and patients alike attach unfair stigmas to "herbal" medicine. Perhaps with whole cannabis extracts, people will be more open to the concept of cannabis as medicine, western style.

As Dr. Russo pointed out, at least we now have a study that emphasizes the benefits of the entire herb over just a few of its chemical components. Cannabis is more that sum of its parts.

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Comment #2 posted by smokeysinse on February 18, 2002 at 10:36:59 PT:

Cannabis Derivatives...
Why do we neeed Cannabis derivatives, when the whole of the herb is just perfect? Just another way of the people who think that they are actually in CONTROL, to tamper & tinker around with something that needs no improvement. Screw them & their derivatives, I will stick to the my buds, FOREVER!

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Comment #1 posted by Ethan Russo MD on February 18, 2002 at 07:06:50 PT:

Site Suggestion/Personal Note
Dear CNews Denizens, Picking up the thread from a prior posting, I would suggest a visit to the GW Pharmaceuticals site:

http://gwpharm.com

Then, click the link under GW plc Preliminary Results for an audio webcast. The "Clinical Update" is of the most interest. This indicates that by September 20, 2001, the company had information on 80 patient-years of use of CMBE (cannabis-based medicine extracts). These produced marked symptom improvement in MS, pain, urinary problems, sleep, etc. Side-effects were minimal. Patients, once stabilized, did not need dosage escalations. Patients are using whole cannabis extracts that include the flavonoids and terpenoids. These emphasize THC or CBD content, or combine the two. These studies go a long way to explaining how cannabis is a much better medicine than oral THC alone (Marinol). This material works very well in patients who have failed all conventional treatments. Cannabis is medicine. Show this data to all who will listen.

A personal note: I have been sparse in my postings of late, but have been lurking in the background. Please rest assured that I am working feverishly on various cannabis-related projects, but have to budget my time more than ever. I will be watching, but only post from time to time. I hope you will all continue your activism.



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