Cannabis News
  DEA Approves UC San Diego Medical Marijuana Study
Posted by FoM on November 29, 2001 at 07:46:25 PT
By Seth Hettena, Associated Press Writer 
Source: Associated Press  

medical The Drug Enforcement Administration granted final approval Wednesday for the first university study on medical marijuana in recent memory. The agency said it hoped to introduce some science into what has been an emotionally-charged debate.

Two professors of neurology at the University of California, San Diego Medical Center will study the effects of marijuana on patients with multiple sclerosis and those who suffer neuropathy, or nerve pain, associated with AIDS.

The studies are the first to emerge out of the Center for Medicinal Cannabis Research at UCSD, a program created by the state Legislature in 1999 to study the medical uses of marijuana.

The studies will involve about 60 people who will be studied over a period of several weeks. All subjects will smoke marijuana cigarettes provided by the National Institute of Drug Abuse in Washington. Half the cigarettes will look and smell like marijuana but will lack THC, the active chemical compound in marijuana.

THC has been available since the 1980s in a synthetic pill form called Marinol, but scientists say it is irregularly absorbed by the stomach.

"The smoking route is being explored not because people want to legalize pot -- that's not our agenda -- but because smoking is an effective way to deliver THC into the blood," said Dr. Igor Grant, director of the Center for Medicinal Cannabis Research, the first program of its kind in the nation.

The DEA's approval reflected the pressure from mounting public opinion that marijuana can ease pain for those who suffer from AIDS, cancer and other illnesses. Since California became the first state to approve medical marijuana in 1996, six other states have followed suit.

"The question of whether marijuana has any legitimate medical purpose should be determined by sound science and medicine," said DEA Administrator Asa Hutchinson.

The agency maintains that past studies have shown no medical benefit to smoking marijuana and that other substances available that can replace the drug. Federal authorities have refused to recognize the initiatives, reasoning that state laws do not apply to federal offenses.

"A lot of these initiatives are just smoke screens -- pardon the pun -- for legalizing drugs," said Donald Thornhill, a spokesman for the DEA in San Diego. He said the studies are part of an attempt to "put this thing to rest."

Opinions are fiercely divided over whether marijuana would help or harm patients, but the scientific community has pointed to a lack of evidence over whether the drug's benefits match its mystique.

The group that promoted California's medical marijuana initiative in 1996 praised the DEA's decision to approve the studies.

"We support any and all continued research into the uses of marijuana for medicinal purposes," said Gina Palencar, a spokeswoman for Santa Monica-based Americans for Medical Rights.

"I don't see how the DEA could hope that any study conducted right now could put the whole issue of medical marijuana to rest," Palencar said. "Unfortunately for the DEA, there's already a body of research that does show therapeutic potential for marijuana for some conditions."

The final approval comes after an exhaustive review process by officials in California and several agencies in Washington: the Department of Health and Human Services, the Food and Drug Administration, NIDA and the DEA.

It will a year before the UCSD studies gather enough data to show whether marijuana has any benefit, Grant said.

"If this method shows that there is something therapeutic, the next step will be to find ways of delivering these products that are socially acceptable," he said.

Source: Associated Press
Author: Seth Hettena, Associated Press Writer
Published: Wednesday, November 28, 2001
Copyright: 2001 Associated Press

Related Articles & Web Site:

Medical Marijuana Information Links
http://freedomtoexhale.com/medical.htm

Researchers Seek Answers on Medical Marijuana
http://cannabisnews.com/news/thread10648.shtml

Medicinal Pot Study Under Way
http://cannabisnews.com/news/thread10537.shtml


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Comment #47 posted by p4me on December 01, 2001 at 00:32:35 PT
website for UCSD
The website for the Center for Medicinal Cannabis Research at the University of California at San Diego is http://www.cmcr.ucsd.edu/

[ Post Comment ]
 
Comment #46 posted by lookinside on November 30, 2001 at 10:13:51 PT:

EJ...
you said it good...i'm grinning...

i wouldn't be a bit surprised if highly evolved plants actually are conscious, but at a much different rate than we are...

as a gardener i've seen things that are hard to explain...

a favorite story: when my oldest daughter was 4 years old, she wanted to plant some carrot seeds in my garden...i gave her a one foot square in the corner of a bed and showed her how to plant them...i planted more in another area about 2 feet away...she went out every day and looked at her carrot patch...pulled the small weeds etc....i was doing the same in the other area...

when time came to dig the carrots, hers were MUCH larger and more uniform than mine...almost 10 pounds of carrots from a 1 foot square patch...did the carrots notice that she really cared about their welfare? i dunno...

[ Post Comment ]

 
Comment #45 posted by FoM on November 30, 2001 at 09:33:12 PT
Just a Note
Hi everyone,

My husband has a Doctor's appointment this afternoon and I can't seem to find any articles to post. The one search tool I use is down and maybe it will be working when we get home.

Have a good day!

[ Post Comment ]

 
Comment #44 posted by FoM on November 30, 2001 at 08:10:15 PT
Patrick
Glad you liked it! That's about the only way they will see it could possibly be socially acceptable! LOL!

[ Post Comment ]
 
Comment #43 posted by dddd on November 30, 2001 at 01:01:12 PT
Far Out!!
.....Thanx again EJ,,,,,that was spectacular!.....you are cool.......sincerely.....4d


on a sad note,,I just saw the news that George Harrison is dead.....12:57 P.M.(Pacific time) Friday

[ Post Comment ]

 
Comment #42 posted by E_Johnson on November 30, 2001 at 00:24:36 PT
lookinside, look inside ;-)
lookinside wrote:

FoM: this is a little different slant on why the "flowers" are the most potent part of the plant... i like to think of a cannabis plant as a reasoning being(the reality is that the plants reactions are the result of a jillion generations of "survival of the fittest")

Okay so this is Evolution 101, I counter it with Geothe 101:

Er nennt's vernunft and braucht's allein,
nur tierischer als jedes Tier zu sein.

He calls it Reason and uses it, resolute,
to be more beastly than the lowest brute

Modern humans are notoriously bad at recognizing emotional states and accounting for them in their "reasoned" decision making processes.

So might we not err when we project a naked inert state of "evolutionary reason" on other living things?

I'm only saying that because one of the things cannabis does for me is relieve the severe emotional numbing common to survivors of trauma. It's like switching from black and white to color in the Wizard of Oz. Oh, so THAT'S what love feels like! Hmmm...

We know about evolution, but correct me if I'm wrong, from what I last read in Science, we don't know all that much about how plants transmit and organize information about their internal states in relation to external conditions.

And we still don't know what consciousness "is" in humans, either.

Maybe the plant feels it, too.



[ Post Comment ]

 
Comment #41 posted by dddd on November 29, 2001 at 23:54:13 PT
anally administered libations
...yes,,and then there is that old song "dont bogart that joint,,my friend"....and the question of,,,"...dont bogart that suppository,my friend,,,pass it on over to me"???,,,no thanks........instead of roachclips,,,will there be 'suppository clips',in our future????dddd

[ Post Comment ]
 
Comment #40 posted by Patrick on November 29, 2001 at 23:33:51 PT
FoM
Oh you silly gal! Suppositories indeed. It will be a cold day in hell before I take my weed up the...

Thanks for the LAUGH!!! I needed one after all the poetry.

[ Post Comment ]

 
Comment #39 posted by FoM on November 29, 2001 at 19:15:53 PT
lookinside
That was a really good way of saying how you see it. It makes sense and thank you. How can a plant so beneficial be so demonized? A nature plant. Grown in the ground and has been on this earth since the beginning of time.

[ Post Comment ]
 
Comment #38 posted by Cannabuzz on November 29, 2001 at 18:28:22 PT
How iz it...
that our government and commercialized-society can so cunningly develope tools and materials for finding minute traces of THC but yet IZ OBLIVIOUS 2 several facts: 1) The marijuana high, from the point of a 'first-timer', is FAR DIFFERENT from the high one gets after their body and mind have adjusted and tolerated the effects of THC and other cannabinoids. In other words, the first couple times someone smokes weed, there will definately be a lot of disorientation, lowered motor-skills, perhaps paranoia. After one has adusted to the effects and knows their dose and tolerance, smoking marijuana becomes highly euphoric, enlightening, energetic or relaxing (depeding upon strain), and infact, enhances all sensory experiences, especially sound, sight, and taste as well as motor-skills. One can even become extremely focused and creative...very thought-provoking at times, too. 2) Science, let alone government-funded science, still has yet to recognize the many differences (especially in medical effect) between pure Sativa's and pure Indica's and the many hundreds of hybrids that produce individual and unique effects. For instance, someone suffering of back pain will need a heavy-hitting Indica plant that gives a narcotic-like and "couch-lock" high(i.e. NorthernLights, Afghani, Romulan, UBC Chemo). Someone who has severe depression with anxiety or chronic fatigue syndrome can greatly benefit from Sativa dominant plants which gives a more energetic "up" high than the Indica's. (i.e. Jack Herer, Thai, Haze, Skunk.) My main point iz!!!: if their going to do this "research project" of their'z in San Diego, they better give 'em the best damn "G13" sticky-ickyness sinsemilla!

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Comment #37 posted by lookinside on November 29, 2001 at 17:56:35 PT:

growers! you might think about this...
FoM: this is a little different slant on why the "flowers" are the most potent part of the plant...

i like to think of a cannabis plant as a reasoning being(the reality is that the plants reactions are the result of a jillion generations of "survival of the fittest")

anyone who has ever grown a pot plant to maturity has seen where and when the resins start to increase on the plant...

cannabis resins are a defense mechanism...when the lady in question notices that the days are growing shorter, she switches from growing stems and leaves to producing flowers...in most areas where cannabis grows naturally, this time coincides with dryness and heat...the resin helps to stop dehydration through the leaves and flowers and to a lesser extent, stems...the plant protects her parts by order of importance...her prime directive is to REPRODUCE, so the flowers get the most attention and resin...the more stressful the conditions, the more resin...this process continues and accelerates until she is polinated, at which point her entire focus is on producing viable seeds...

this is why seeded pot is generally weaker in THC than sinsimilla..(and why the boys end up in the compost pile at the first indication they are boys!)

the psychoactive compounds seem to be a defense against pests...i've noticed that a slug or snail will crawl all over a flower top and never take a nibble, yet will skeletonize an older and yellowing sunleaf farther down the plant...( in my area there is one tiny caterpillar that seems to have adapted to the resin...they are VERY active and if not caught quickly, will destroy an entire top in short order...)

a deer or rabbit would be less inclined to decimate a mature plant than a young green one...(stoned bunnies are easy coyote food)

because research is hard to find, i'm speaking mostly from personal observation...hope this helps a little...

in my experience as a gardener, i've never seen any plant to match the beauty, versatility and perfection of the cannabis plant...and mother nature had it perfected long before we had fire...

[ Post Comment ]

 
Comment #36 posted by mayan on November 29, 2001 at 15:38:35 PT
The DEA's Not Biased Are They?
"A lot of these initiatives are just smoke screens -- pardon the pun -- for legalizing drugs," said Donald Thornhill,a spokesman for the DEA in San Diego. He said the studies are an attempt to "put this thing to rest."

Isn't that statement an admission that these studies are rigged? They probably have the results of these studies predetermined! The Fed's are going to give these guinea pigs some twigs & beans to choke on so they can get the results they want. What a bunch of sh*t!

"Suit Challenges Bush Executive Order" http://dailynews.yahoo.com/h/ap/20011128/pl/presidential_papers_lawsuit_2.html

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Comment #35 posted by E_Johnson on November 29, 2001 at 14:33:30 PT
Shakespeare on the Ashcroft administration
From the Merchant of Venice:

Mark you this, Bassanio,
The devil can cite Scripture for his purpose.
An evil soul producing holy witness
Is like a villain with a smiling cheek,
A goodly apple rotten at the heart:
O, what a goodly outside falsehood hath!



[ Post Comment ]

 
Comment #34 posted by FoM on November 29, 2001 at 13:53:35 PT
Socially Acceptable
"If this method shows that there is something therapeutic, the next step will be to find ways of delivering these products that are socially acceptable," he said.

Socially acceptable? Can you see us all at a cocktail party and trying to talk about how we use our new found legal medicine.

I can see it all now.

You use Cannabis?

Yes!

How pray tell?

A wonderful suppository!

[ Post Comment ]

 
Comment #33 posted by Zero_G on November 29, 2001 at 13:32:10 PT:

Rabelais
Speaking about Cannabis: (called here Pantagruelion)

[...]so in Pantagruelion I recognize so many virtues, so much vigor, so many admirable effects, that if its full worth had been known when, as the Prophet tells us, the trees elected a wooden king to reign over them and govern them, it would no doubt have gained the majority of their votes and sufferages. Shall I go further? ...

Gargantua and Pantagruel

Rabelais 1490-1553

[ Post Comment ]

 
Comment #32 posted by E_Johnson on November 29, 2001 at 13:05:24 PT
Shakespeare, pot and alchemy
One of the spritual peregrinations that I think marijuana has led me into has been playing with the Alchemical Tarot. As a means of self-exploration.

Because of that I've learned some of the language and ideas of alchemy and I think the XXIXth sonnet is loaded with them.

Shakespeare in this sonnet could be describing the Fool's journey through blindness and self-ignorance and preoccuation with the material, into the state of enlightenment, self-knowledge and the attainment of the spiritual memory of the World, the Quinta Essentia.

And here's what they found in his garden -- evidence that could get him criminally charged with paraphernalia and residue:

http://news.nationalgeographic.com/news/2001/03/0301_shakespeare.html

Shakespeare, Bob Marley, Louis Armstrong...

No wonder the powers that be want the weed dead.

If you read enough Shakespeare, you'll realize what an dangerous project government is in its conception, how only individual kindness and the search for spirtual grace guarantees that civilization is sustainable.

Laws both harm and help, as we learn in Merchant of Venice. Portia had to spin the law pretty hard to keep her lover from losing that pound of flesh he agreed to in a written contract.

The quality of mercy is NOT strained!

That's a Shakespearean manifesto before which the Ashcroft administration ought to tremble at the knees.



[ Post Comment ]

 
Comment #31 posted by Zero_G on November 29, 2001 at 12:55:43 PT:

E_J Science & Spirituality
I'd like to see some scientific research about marijuana and the human sensation of spirituality.

Tracing the Synapses of Our Spirituality Researchers Examine Relationship Between Brain and Religion By Shankar Vedantam, Washington Post Sunday, June 17, 2001

full article at: http://www.maps.org/media/vedantam.html

In Philadelphia, a researcher discovers areas of the brain that are activated during meditation. At two other universities in San Diego and North Carolina, doctors study how epilepsy and certain hallucinogenic drugs can produce religious epiphanies. And in Canada, a neuroscientist fits people with magnetized helmets that produce "spiritual" experiences for the secular. The work is part of a broad effort by scientists around the world to better understand religious experiences, measure them, and even reproduce them. Using powerful brain imaging technology, researchers are exploring what mystics call nirvana, and what Christians describe as a state of grace. Scientists are asking whether spirituality can be explained in terms of neural networks, neurotransmitters and brain chemistry.[...]

------------------------------------------------------------

For a good exploration of the History of Cannabis and spirituality:

Green Gold; Marijuana in Magick and Religion

Chris Bennet, Lynn and Judy Osbourne

------------------------------------------------------------

Also, you may be interested in the work of Dr. Charles Tart, who has put together the TASTE website:

http://www.issc-taste.org/index.shtml

The Archives of Scientists Trancendent Experiences

Zero G

[ Post Comment ]

 
Comment #30 posted by FoM on November 29, 2001 at 12:18:48 PT
Doctor Visit
Tomorrow my husband goes for a 6 month check up and I dread it. I know what he will say to us. We still don't know what is wrong. More tests. That will be it. The Doctor said no herbs because it could get him sick. I stopped giving my husband Milk Thistle and he got sick. I said fooey and put him back on Milk Thistle and a few supplements and he hasn't gotten sick near as often or as severe. What I'm afraid will happen is he is a tobacco hating Doctor and blames everything on tobacco. Smoing isn't the only cause of some illnesses.

PS: Yoo Hoo Dr. Russo you don't count in this!

[ Post Comment ]

 
Comment #29 posted by E_Johnson on November 29, 2001 at 12:04:42 PT
It's a greater crisis, I agree
I know what you mean about the medical system. I get 15 minutes with a doctor in a typical appointment-- what meaningful exachange of information can happen in that time frame?

Last year I had a bladder infection and the doctor treated me with Levaquin without warning me of the severe side effects of this drug. When I called back and said I was having mood swings with paranoid delusions she had no idea what to say. Then I got on the Internet and found out these are known side effects of this antibiotic and also it can cause arthritic lesions in the joints and sponataneous tendon rupture.

The doctor had no idea!

She was handing out this dangerous drug like it was nothing, and apparently didn't know any more about it than came on the corporate brochure from the sales rep who visits her once a month.

And medical marijuana is claimed to be a suspect operation. Indeed.



[ Post Comment ]

 
Comment #28 posted by FoM on November 29, 2001 at 11:54:42 PT
Dr. Russo
Do you want the pdf file you sent me to be on line? If so I think I finally figured out how to do it. Let me know when you have time.

[ Post Comment ]
 
Comment #27 posted by Sam Adams on November 29, 2001 at 11:42:42 PT
AP BS
Another DEA press release cloaked as an AP "news" article! Disgraceful.

Sorry Dr. Russo, but I respectfully disagree - I don't think there's "ignorance" on the part of doctors who recommend against higher potency cannabis. I think the DEA is carefully approving only studies within parameters that will give the highest possible chance of a negative result. The whole framework and various approval processes for cannabis studies in the US is one big exercise in mental masturbation. Anyone can go on pubmed and in 30 seconds pull down an abstract of studies showing a 97% efficacy rate of cannabis with MS. Any moron who has functioning brain can figure out that higher potency means less combustion byproducts per active ingredient. Don't let these tyrants off so easily.

The approval board said higher potency would be "toxic"? Cannabis has 0 toxicity! Again, confirmed by many readily available, tightly controlled studies over the last 200 years. How many on that board are Southern, politically-connected appointees? How many had fathers and grandfathers who held the rope at the weekly town lynchings just a few decades ago?

When the government disagrees with the blatant factual truth of any issue, there is a simple routine they go through to create "controversy". They cling to the minority of biased research showing their point of view and trumpet the results. They say the subject needs "more study". The shameless whores of the media then validate the propaganda by claiming a "controversy" or a scientific establishment "fiercely divided" on the issue. Just look at global warming...over 95% of climatological scientists agree that it will happen. 2500 signed a pact pleading for action on the issue! Every other Western government in the world wants to move ahead! But our media consistently reports it as an unresolved issue. Partially because they're just a government/corporate mouthpiece, and partially because any story is better with a well-matched "pro" and "con".

I guess part of what angers me with on this is the arrogance of the entire medical establishment. They've never based their practice on helping the patient to achieve the best lifestyle possible. Instead, Western medicine is a kind of ego-worship of the physician as some sort of all-powerful arbiter of medical science. Many specialists and surgeons aren't out to help patients, they're out to prove their own superiority and skill to the medical world. Why do nurses groups consistently and staunchly support medical marijuana while the AMA condemns it?

If you talk to an herbal medicine practitioner, you will find that the most of the medical cannabis issues are replicated for the entire field of herbal medicine. Doctors fretting about controlling dosage, extracting and standardizing active ingredients, doctors not understanding the synergistic effect of more that one active ingredient, lamenting the dearth of controlled, large scale studies, etc, etc, etc, etc!

I see only the reality. They help many people, but doctors and drug makers kill and maim thousands upon thousands of people each year with their pills and drugs. People have a FUNDAMENTAL RIGHT to treat themselves for their problems however they see fit! Does being a member of modern society mean that you cede all decision-making and control of your own health over to a board-certified doctor? Let's call a spade a spade...the current situation, in the US in Canada, is patently absurd. We have million of dollars of government resources going towards growing poor-quality schwag, while thousands of people quickly, easily, and cheaply grow extremely high-quality, effective cannabis in every neighborhood of every region of the continent! Legitimately sick people are hiding green plants in elaborate and expensive schemes in basements, attics, bureaus, closets and hidden compartments like some kind of botanical underground railroad.

It's one of the biggest travesties of modern times. I can't understand why those that fund referendums don't quickly move to pass prop215 type laws in every state of the union. Why on Earth would one want to tangle with courts, a fucked-up medical system, or government bureaucracies? end of ranting for today.....

[ Post Comment ]

 
Comment #25 posted by E_Johnson on November 29, 2001 at 11:31:56 PT
This is a patently ridiculous statement
Opinions are fiercely divided over whether marijuana would help or harm patients, but the scientific community has pointed to a lack of evidence over whether the drug's benefits match its mystique.

What direction can you point in when while cowering in a corner protecting your own behind?



[ Post Comment ]

 
Comment #24 posted by E_Johnson on November 29, 2001 at 11:31:24 PT
This is a patently ridiculous statement

What direction can you point in when while cowering in a corner protecting your own behind?



[ Post Comment ]

 
Comment #23 posted by freedom fighter on November 29, 2001 at 11:23:39 PT
I hope the study be subject to peer review
I really think this study is completely biased and downright dangerous.

Man, that's cruel..

ff

[ Post Comment ]

 
Comment #22 posted by E_Johnson on November 29, 2001 at 11:19:48 PT
That sonnet always bothered me
When human beings are feeling depressed and feeling loss of self esteem and identity, I've never heard that it helps to remember a former lover whom you can't be around any more.

It doesn't really make a lot of emotional sense if he's talking about a real human lover.

It's either about religion or pot or both I think.

Haply I think on thee -- it could mean he's just lighting up.

Thy sweet love remembered -- now he's fully feeling the effects.

The sonnet seems to be about being enspirited after being despirited. But what is the agent of this transformation? I don't believe it's really a human agent.

We know now that someone was smoking weed near where he used to live at the time when he lived there. They found a pipe with cannabis residue in it.

I'd like to see some scientific research about marijuana and the human sensation of spirituality.

[ Post Comment ]

 
Comment #21 posted by E_Johnson on November 29, 2001 at 10:59:55 PT
It's BAD to make sick people smoke THC-free weed!
The research that has been done at UCLA into the cellular processes by which marijuana tar could cause lug cancer has revealed that THC molecules prevent the aryl hydrocarbon receptors from processing the carcinogens in the tar by blocking the aryl hydrocarbon receptors in a dose-dependent manner.

http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11245634&dopt=Abstract

The THC molecules sit in the places in the cell where the carcinogens are supposed to sit in order to pass their cancer-causing information into the cell.

In a dose-dependent manner -- this means that the MORE THC in the weed, the FEWER sites in the cell the carcinogens can find to be fit into.

So giving sick people NIDA dirt weed is a really bad idea!!!!!! Dangerous. Irresponsibly dangerous.

To the point that researchers need to start examining their ethics in this project. Complying with the requirement to use NIDA marijuana could really constitute be a breach of ethics against the subjects in the research.

If there are ever any federal safety standards to protect marijuana smokers from lung cancer, those standards should mandate a minimum, not a maximum, THC content!!

Which would probably put all of NIDA in a state of violation.



[ Post Comment ]

 
Comment #20 posted by Ethan Russo MD on November 29, 2001 at 10:53:39 PT:

Good Riff
And a good riff 'twas, dear E_J!

[ Post Comment ]
 
Comment #19 posted by FoM on November 29, 2001 at 10:53:16 PT
EJ Thanks
Now I see it. I was concentrating on the flowers and resin I was wondering about and missed that and now I see. I still don't understand but I'm learning I think.

[ Post Comment ]
 
Comment #18 posted by E_Johnson on November 29, 2001 at 10:46:34 PT
That's Ethan's quote not mine
That's what Ethan Russo, MD, wrote. I was just riffing on it a bit in relation to Queen Elizabeth.



[ Post Comment ]

 
Comment #17 posted by FoM on November 29, 2001 at 10:35:01 PT
EJ Thanks
The potency and quality of cannabis depend on its genetics and cultural practices. Altitude, heat and intense light all increase cannabinoid production, but keeping the flowers unfertilized synergizes the process. That is why I call cannabis Nature's highest expression of unrequited female botanical passion.

That's nice.

[ Post Comment ]

 
Comment #16 posted by E_Johnson on November 29, 2001 at 10:29:52 PT
The Virgin Queen -- the 29th Sonnet!!
The potency and quality of cannabis depend on its genetics and cultural practices. Altitude, heat and intense light all increase cannabinoid production, but keeping the flowers unfertilized synergizes the process. That is why I call cannabis Nature's highest expression of unrequited female botanical passion.

Sounds like the Elizabethan era in England. The Virgin Queen and all that.

Maybe Shakespeares mystery women in the XXIXth Sonnett is Lady Cannabis?

When in disgrace with fortune and men's eyes

I all alone beweep my outcast state,

And trouble deaf heaven with my bootless cries,

And look upon myself, and curse my fate,

Wishing me like to one more rich in hope,

Featured like him, like him with friends possessed,

Desiring this man's art, and that man's scope,

With what I most enjoy contented least;

Yet in these thoughts my self almost despising,

Haply I think on thee, and then my state,

Like to the lark at break of day arising

From sullen earth, sings hymns at heaven's gate;

For thy sweet love remembered such wealth brings

That then I scorn to change my state with kings.

[ Post Comment ]

 
Comment #15 posted by FoM on November 29, 2001 at 10:25:46 PT
For Those Who Don't Know The Song
from: Dr. Demento's Delights
Warner Bros. 1975 BS 2855 0698

Remember when you ran away and I got on my knees and begged you not to
leave because I'd go berserk?? Well...
You left me anyhow and then the days got worse and worse and now you see
I've gone completely out of my mind.. And..
They're coming to take me away, ha-haaa!!
They're coming to take me away, ho-ho, hee-hee, ha-haaa
To the funny farm. Where life is beautiful all the time and I'll be
happy to see those nice young men in their clean white coats and they're
coming to take me away, ha-haaa!!!!!

You thought it was a joke and so you laughed, you laughed when I had said
that loosing you would make me flip my lid.. RIGHT???
I know you laughed, I heard you laugh, you laughed you laughed and
laughed and then you left, but now you know I'm utterly mad... And..

They're coming to take me away, ha-haaa,
They're coming to take me away, ho-ho, hee-hee, ha-haaa.
To the happy home. With trees and flowers and chirping birds and basket
weavers who sit and smile and twiddle their thumbs and toes and they're
coming to take me away, ha-haaa!!!

I cooked your food, I cleaned your house, and this is how you pay me back
for all my kind unselfish loving deeds.. Huh??
Well you just wait, they'll find you yet and when they do they'll put you
in the ASPCA, you mangy mutt!!! And...

They're coming to take me away, ha-haaa.
They're coming to take me away, ho-ho, hee-hee, ha-haaa.
To the funny farm, where life is beautiful all the time and I'll be happy
to see those nice young men in their clean white coats and they're coming
to take me away, ha-haaa!!!
To the happy home, with trees and flowers and chirping birds and basket
weavers who sit and smile and twiddle their thumbs and toes and they're
coming to take me away, ha-haa!!!
To the funny farm, where life is beautiful all the time... (fade out)

Hey, buddy!
Yes officer..
You a head?
No, but I'm catching up, ha ha ha....

original recording by Napoleon XIV

[ Post Comment ]
 
Comment #14 posted by E_Johnson on November 29, 2001 at 10:22:32 PT
ALL of the cigarettes, from what we hear
All subjects will smoke marijuana cigarettes provided by the National Institute of Drug Abuse in Washington. Half the cigarettes will look and smell like marijuana but will lack THC, the active chemical compound in marijuana.

From what we've heard of noxious NIDA dirt weed in the San Mateo study, I think it's safe to say that NONE of the cigarettes will look and smell like marijuana, and ALL of them will be will lack enough THC to matter for the purposes of the study.

With all of the skilled and experienced marijuana growers that we have confined in federal custody in this country -- why is it that NIDA is incapable of producing marijuana of medicinal quality?

I'll bet they don't even know how to separate the males from the females. They're pathetic. The only thing they know how to do well over there is locate traces of cannabinoids in the urine of citizens.



[ Post Comment ]

 
Comment #13 posted by CongressmnSuet on November 29, 2001 at 09:56:45 PT
" They are coming to take me away..."
Thanks, Fom! Thats the first time in years I have heard anybody quote from Napolean and The Bonapartes smash hit! Do you rememer, if you turned the 45 over the song played backwards? Do you also remember that the cause of the singers breakdown was actually his lack of a good relationship with his "Mutt"? As to this study....forget about it! This deck is stacked as high as Mount Arafat! This has been in the planning for some time, and we can expect some bizarre results when all is aid and done. Besides, even if it was an honest study, the results, like the IOM study, will only be tossed aside. They are just buying time...

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Comment #12 posted by FoM on November 29, 2001 at 09:27:12 PT
Can you hear me screaming?
Just kidding. But these days as I go about life I hum this.

They're coming to take me away ha ha ho ho to the funny farm where life is beautiful all the time! LOL!

It's not that bad but splitting hairs like our government loves to do is drivng me CRAZY.

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Comment #11 posted by Sudaca on November 29, 2001 at 09:17:08 PT
will they get high?
Isn't it rather cruel to give ditchweed to people with disabling sicknesses; who are looking for relief by smoking? To dose them with something that will provide no relief at all just to use them as a "control group"? Are they trying to prove that pot is a placebo? Wouldn't a better control group be people who are not given anything to smoke, or who are treated with conventional medicines?

What if they slip their low potency pot into the placebo group and then claim that they just "think" they're high?

What's wrong with the studies published in Britain about MS, what's wrong with other studies in other places where there's a less emotional devate going on? As in hysterical prohibitionists hanging by their toenails to the gravy train vs outraged horrified people who can't believe the monsters that sit in power?

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Comment #10 posted by Patrick on November 29, 2001 at 09:08:16 PT
HOLY COW!!!
Asa Hutchinson said...

"The question of whether marijuana has any legitimate medical purpose should be determined by sound science and medicine."

Wow I guess those debates with Guv Johnson are rubbing off on him finally. Perhaps, he finally got around to reading his copy of the Constitution? In any event, I still fear that the guvment will suppress any results that don't support the view that cannabis is evil.

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Comment #9 posted by FoM on November 29, 2001 at 09:06:35 PT
Thanks Dr. Russo
I think I understand. Please sent me the pdf file. So if I read what you are saying correctly it is the flowers but the resin is important too. This is confusing but interesting. Thanks.

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Comment #8 posted by Ethan Russo MD on November 29, 2001 at 09:00:26 PT:

The Real Right Stuff
All of the major medicinal properties of cannabis derive from the glandular trichomes. These are modified "hairs" or stalked structures on the unfertilized flowers, bracts, and to a lesser extent, the leaves. At the end of these, a phytochemical factory produces the resin, that contains THC, other cannabinoids, and the terpenoids that give cannabis its smell and contribute to its medicinal properties.

All of the "awe" is in there.

The potency and quality of cannabis depend on its genetics and cultural practices. Altitude, heat and intense light all increase cannabinoid production, but keeping the flowers unfertilized synergizes the process. That is why I call cannabis Nature's highest expression of unrequited female botanical passion.

For pictures and text that help, I'd strongly recommend Rob Clarke's book, Hashish!

For more technical information on cannabis components and their medical contributions, people can E-mail me for a PDF file of the article John McPartland and I wrote, "Cannabis and cannabis extracts: Greater than the sum of their parts?"

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Comment #7 posted by Robbie on November 29, 2001 at 09:00:15 PT
NIDA smoke
Since the DEA and NIDA are actively anti-marijuana, wouldn't any independent view dictate that the vested interests of these organizations are not served by the success of any study that might find them at odds with their mission? MMJ researchers are genuine in their desire to get the hard facts, but low grade schwag from NIDA precludes any possibility that the benefits of cannabis are truly understood in these studies.

Ethan Russo, is there any organization that could intercede on behalf of researchers and justify the use of varied strains and potencies? Or would this all end up as another court-determined issue?

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Comment #6 posted by krutch on November 29, 2001 at 08:56:17 PT:

This Study is Suspect
I am suspicious of any study that is undertaken to to "put this thing to rest".

A study should be undertaken with no preconceived notions about what conclusions will be drawn from the results.

While I agree with Dr, Russo that this is start, I would not be suprised if the results are that MJ is of no medical value. The deck seems to be stacked that way already.

I am also curious about this double speak:

"The agency maintains that past studies have shown no medical benefit to smoking marijuana and that other substances available that can replace the drug."

If no medical benefit comes from MJ then what do the other substances that can replace it do?



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Comment #5 posted by FoM on November 29, 2001 at 08:48:24 PT
Question
Now this might sound really, really dumb but I'll ask anyway. What part of the plant contains most of the "awe" stuff? I've read people rave about a resinous plant but I thought it was the flowers not the resin. See I don't know. I thought resin was produced to try to catch pollen so the plant could get fertilized but I'm not sure at all. Thanks for any advice.

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Comment #4 posted by Ethan Russo MD on November 29, 2001 at 08:37:14 PT:

Clarification
The problems with these studies are not the fault of the researchers. NIDA's pre-rolled cannabis cigarettes are usually in the 2-4% THC range and are laden with stems and seeds.

Recently, NIDA announced the availability of 7% THC cannabis, but when Dr. Donald Abrams tried to suggest its use for his clinical trials, the investigational review board thought that material so potent would be toxic, and denied approval.

Where cannabis is concerned, there is more than enough ignorance to go around. We all need to help change that situation.

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Comment #3 posted by p4me on November 29, 2001 at 08:23:26 PT:

research starting now
The continued stay of MJ on the list of Schedule 1 narcotics means that there is no medical use the substance. Where is the research they used in coming to this conclusion?

Half the cigarettes will look and smell like marijuana but will lack THC, the active chemical compound in marijuana.

I sure hope people do not notice the difference between orageno weed and real MJ. They might lie to distort the findings and render the whole study useless. I agree with Dr. Russo that they should use medical grade cannabis since that is what should be used for the real-life patients. And then again they should promote the use of vaporizers and also conduct seperate studies on the method of use issues alone. Only ignorance could have launched a study with such a flawed trajectory. More stupidity by our not so friendly servants at the DEA.

The land of the free is the land of pee.

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Comment #2 posted by JR Bob Dobbs on November 29, 2001 at 08:17:06 PT
HALF?
>>The studies will involve about 60 people who will be studied over a period of several weeks. All subjects will smoke marijuana cigarettes provided by the National Institute of Drug Abuse in Washington. Half the cigarettes will look and smell like marijuana but will lack THC, the active chemical compound in marijuana.<<

From the way I've always heard it, the government cannabis ALL looks and smells like marijuana but lacks THC. Maybe it has SOME, but it's certainly not in copious quantities.

Well hey, if you study it like this... "Look, nobody's ever gotten cirrhosis from drinking O'Doul's! Therefore, alcohol does not cause cirrhosis!"

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Comment #1 posted by Ethan Russo MD on November 29, 2001 at 07:55:46 PT:

It's a Start
I am glad that this long overdue approval by the DEA has finally come to pass.

As to putting the issue to rest, doesn't that assume a negative result? That would be unlikely in any event.

These studies will be subject to numerous disclaimers:

The NIDA material is weak in THC and other cannabinoids and terpenoids as compared to true medical grade cannabis.

The side effect profile of NIDA cannabis is one of highly irritating smoke with subsequent throat and pulmonary issues. This is once more, not representative of medical grade cannabis.

More importantly, smoked cannabis is not the only method to administer the herb, nor is it the best from a medical standpoint. No research on vaporization, sublingual tinctures or other alternative methods has been approved in the USA.

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